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This medicine is known as sertraline. Exercise has many benefits for older adults and can help you to live a longer and healthier life.

Go PRO to access past versions. Pregnancy Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants during pregnancy. Risk Summary Based on data from published observational studies, exposure to SSRIs, particularly in the month before delivery, has been associated with less than 2-fold increase in the risk of postpartum hemorrhage [see Warnings and Precautions 5. Overall, available published epidemiologic studies of pregnant women exposed to sertraline in the first trimester suggest no difference in major birth defect risk compared to the background rate for major birth defects in comparator populations. Some studies have reported increases for specific major birth defects; however, these study results are inconclusive [See Data].

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If you are a consumer or patient please visit this version. Antidepressants increased the risk compared to placebo of suicidal thinking and behavior suicidality in children, adolescents, and young adults in short-term studies of major depressive disorder MDD and other psychiatric disorders. Anyone considering the use of Sertraline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Sertraline hydrochloride tablets are not approved for the treatment of major depressive disorder in pediatric patients. Sertraline hydrochloride is a selective serotonin reuptake inhibitor SSRI for oral administration. It has a molecular weight of Sertraline hydrochloride has the following chemical name: 1S-cis 3,4-dichlorophenyl -1,2,3,4-tetrahydro-N-methylnaphthalenamine hydrochloride. Sertraline hydrochloride is a white crystalline powder that is slightly soluble in water and isopropyl alcohol and sparingly soluble in ethanol. The mechanism of action of sertraline is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin 5HT. Studies at clinically relevant doses in man have demonstrated that sertraline blocks the uptake of serotonin into human platelets. In vitro studies in animals also suggest that sertraline is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptake.

Sertraline hydrochloride may cause serious side effects, blue oval pill 213, including: See " What is the most important information I should know about Sertraline hydrochloride? No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible.

I believe the Ig 23 should not be labeled as ' Xanax ' as it is highly misleading. There is no way it can be considered a Xanax. The introduction of these new drug brands is extremely confusing, particularly for older individuals. It's no surprise that my dad double-checks the markings on his Xanax pills! Hello, Missyboo! How are you? The blue, oval tablet with the marking IG is manufactured by Camber Pharmaceuticals and they list it as containing 50mgs of Sertraline , which is an SSRI antidepressant.

This medicine is known as sertraline. Exercise has many benefits for older adults and can help you to live a longer and healthier life. Here are 6 benefits of exercise for older adults and seniors. Exercise has many benefits on physical and mental health wellbeing. A few minutes of physical activity a day can have a positive impact on your mood.

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Controlled Substance Class — Sertraline hydrochloride is not a controlled substance. The effectiveness of sertraline in long-term use, that is, for more than 3 menstrual cycles, has not been systematically evaluated in controlled trials. Sertraline hydrochloride treatment initiated during the acute phase of recovery within 30 days post-MI or post-hospitalization for unstable angina was indistinguishable from placebo in this study on the following week 16 treatment endpoints: left ventricular ejection fraction, total cardiovascular events angina, chest pain, edema, palpitations, syncope, postural dizziness, CHF, MI, tachycardia, bradycardia, and changes in BP , and major cardiovascular events involving death or requiring hospitalization for MI, CHF, stroke, or angina. Drugs Metabolized by CYP3A4 In three separate in vivo interaction studies, sertraline was co-administered with CYP3A4 substrates, terfenadine, carbamazepine, or cisapride under steady-state conditions. The drug-placebo differences in the number of cases of suicidal thoughts and behaviors per 1, patients treated are provided in Table 2. Major Depressive Disorder The efficacy of sertraline as a treatment for major depressive disorder was established in two placebo-controlled studies in adult outpatients meeting DSM-III criteria for major depressive disorder. In managing overdosage, consider the possibility of multiple drug involvement. Hello, Missyboo! Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid. Serotonergic Drugs Based on the mechanism of action of SNRIs and SSRIs, including sertraline hydrochloride, and the potential for serotonin syndrome, caution is advised when SNRIs and SSRIs, including sertraline hydrochloride, are coadministered with other drugs that may affect the serotonergic neutrotransmitter systems, such as triptans, linezolid an antibiotic which is a reversible non-selective MAOI , lithium, tramadol, or St. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Geriatric Use —U. No suicides occurred in any of the pediatric trials. One of these additional studies was conducted in patients similar to those recruited for Studies 1 and 2, while the second additional study was conducted in predominantly male veterans.

Specifically, pharmacists have access to drug information from a variety of resources, including print publications, subscription-based electronic databases e. Thus, when searching for drug information, many times the problem facing a pharmacist is not a lack of resources, but rather too many resources from which to choose. Its availability, ease of use, contents, and legal weight make the PI the resource that should often be the starting point when initiating a search for drug information.

Labor and Delivery —The effect of sertraline hydrochloride on labor and delivery in humans is unknown. The physician should consider contacting a poison control center on the treatment of any overdose. Endocrine Disorders— Rare: exophthalmos, gynecomastia. A PTSD diagnosis requires that the symptoms are present for at least a month and that they cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. Social Anxiety Disorder — Sertraline hydrochloride is indicated for the treatment of social anxiety disorder, also known as social phobia in adults. Families and caregivers of patients being treated with antidepressants for major depressive disorder or other indications, both psychiatric and nonpsychiatric, should be alerted about the need to monitor patients for the emergence of agitation, irritability, unusual changes in behavior, and the other symptoms described above, as well as the emergence of suicidality, and to report such symptoms immediately to health care providers. While there have been reports of abnormal bleeding or purpura in several patients taking sertraline hydrochloride, it is unclear whether sertraline hydrochloride had a causative role. Male and Female Sexual Dysfunction with SSRIs Although changes in sexual desire, sexual performance and sexual satisfaction often occur as manifestations of a psychiatric disorder, they may also be a consequence of pharmacologic treatment. Pharmacokinetics Systemic Bioavailability —In man, following oral once-daily dosing over the range of 50 to mg for 14 days, mean peak plasma concentrations C max of sertraline occurred between 4. Accordingly, prothrombin time should be carefully monitored when sertraline therapy is initiated or stopped.