Glove and stocking pattern

The peripheral nerves consist of bundles of long neuronal axons as they exit the central nervous system CNS. Some peripheral nerves glove and stocking pattern wrapped in a myelin sheath generated by Schwann cells, whereas others are unmyelinated. Peripheral nerves serve different motor, sensory, and autonomic functions. The term peripheral neuropathy is usually used to describe symmetric and universal damage to adjacent nerves.

Stocking glove neuropathy refers to symptoms of peripheral neuropathy that cause numbness, weakness, or sensory changes in the hands and feet. It has a number of potential causes, including diabetes. Peripheral neuropathy is nerve damage to the peripheral nerves. These nerves send signals throughout the body and to the brain and spinal cord , also known as the central nervous system. Some types of peripheral neuropathy start in the hands and feet. Doctors call this stocking and glove distribution, as people may feel as though they are wearing stockings and gloves when they are not. This article explains what stocking glove neuropathy is, its symptoms, causes, and treatment options.

Glove and stocking pattern

In the Western world, diabetes is the biggest cause of peripheral neuropathy, usually distal symmetric polyneuropathy but some times another polyneuropathy or a focal neuropathy. In addition, hypothyroidism and acromegaly can cause carpal tunnel syndrome and other sensory complaints. A complete blood cell count, nerve-conduction tests, thyroid-function tests needed in all patients with carpal tunnel syndrome , and when necessary, needle electromyography can help confirm the diagnosis. Treatment of underlying disease is the most successful management approach: Tight glucose control in diabetic patients, thyroid hormone replacement therapy in patients with hypothyroidism, and removal of the pituitary adenoma in patients with acromegaly are of proven benefit. Significant symptomatic relief of dysesthesias can be obtained with use of capsaicin cream, tricyclic antidepresants, anticonvulsant agents, or an antiarrhythmic drug. Abstract In the Western world, diabetes is the biggest cause of peripheral neuropathy, usually distal symmetric polyneuropathy but some times another polyneuropathy or a focal neuropathy. Publication types Review.

Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. The data follow the FDA approval of omalizumab for the reduction of allergic reactions, including anaphylaxis, that can occur after exposure to 1 or more foods, glove and stocking pattern.

Many patients presenting themselves with complaints of numbness or weakness will eventually be shown to have a disorder of the peripheral nervous system. Although the differential diagnosis is large in these disorders, the combination of a directed neurologic history exam along with relatively simple ancillary testing will quickly narrow the differential diagnosis. As many of these disorders are treatable or curable, prompt recognition, especially early in the clinical course, is important. Peripheral neuropathies a. Many disease processes may preferentially attack either the axon or the myelin sheath of the peripheral nerve. As a rule, axonal peripheral neuropathies affect the longest axons first.

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Glove and stocking pattern

Stocking glove neuropathy refers to symptoms of peripheral neuropathy that cause numbness, weakness, or sensory changes in the hands and feet. It has a number of potential causes, including diabetes. Peripheral neuropathy is nerve damage to the peripheral nerves.

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In disorders that cause acute peripheral neuropathy, such as those produced by toxic exposures, patients may present with similar but more fulminant symptoms, and pain predominates; symptoms also typically have a faster progression. Nervous system Cardiovascular system Respiratory system Digestive system Immune system. EMG can detect active axonal damage, as evidenced by the presence of spontaneous muscle fiber activity at rest resulting from the absence of neuro-regulation denervation. Nerve biopsy should be considered when the diagnosis remains uncertain after laboratory and electrodiagnostic testing, or when confirmation of the diagnosis is needed before initiating aggressive treatment e. The most common toxin is alcohol. Clin Ther. Transport of proteins and nutrients from the cell body is affected early, with subsequent breakdown and loss of the most distal peripheral nerve fibers. Nerve conduction studies assess the shape, amplitude, latency, and conduction velocity of an electrical signal conducted over the tested nerve. Fasciculations Myokymia Cramps. In the United States, diabetes is the main cause of neuropathy affecting multiple nerves in the peripheral nervous system. Find out how long diabetic neuropathy takes to develop.

However, numbness in the clinical context refers to loss of sensation, either partial hypesthesia or complete anesthesia. Clinicians must determine exactly what a patient means by the term weakness. Numbness may involve some or all of the three major sensory modalities to the same or different degrees:.

Normal nerve conduction studies and needle EMG significantly decrease the likelihood of peripheral neuropathy, whereas abnormal nerve conduction findings confirm the diagnosis. A doctor may also order blood tests to check for underlying medical conditions, such as diabetes, vitamin deficiencies, or autoimmune conditions. In more severe cases, sensory loss may be found over the anterior chest and abdomen, reflecting degeneration of the distal thoracic intercostal nerves. Medical News Today. Electromyography EMG and Nerve Conduction Studies NCS can help clarify the exact localization of the lesion and will often suggest the underlying type of pathology axonal or demyelinating. Sensory Large Fiber. Human Biology. J Neurol Neurosurg Psychiatry. Some peripheral nerves are wrapped in a myelin sheath generated by Schwann cells, whereas others are unmyelinated. Clinical evaluation and investigation of neuropathy. Such a finding readily narrows the differential diagnosis. People may experience mild or severe symptoms, depending on the type and extent of nerve damage.