Granisetron hydrochloride syrup uses

Granisetron is a serotonin 5-HT 3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and radiotherapy. Its main effect is to reduce the activity of the vagus nervewhich is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness, granisetron hydrochloride syrup uses.

Information about Granisetron Granisetron Uses Granisetron is used to prevent nausea and vomiting due to chemotherapy. How Granisetron works Granisetron is an antiemetic medication. It works by blocking the action of a chemical messenger serotonin in the brain that may cause nausea and vomiting during anti-cancer treatment chemotherapy or after surgery. Anuj Saini. Varun Gupta. We provide you with authentic, trustworthy and revelant information Want to know more.

Granisetron hydrochloride syrup uses

Official websites use. Share sensitive information only on official, secure websites. Granisetron is used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. Granisetron is in a class of medications called 5-HT 3 receptor antagonists. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Granisetron comes as a tablet to take by mouth. When taken to prevent nausea and vomiting caused by chemotherapy, granisetron is usually taken 1 hour before chemotherapy is begun. A second dose may be taken 12 hours after the first dose depending on the strength. When taken to prevent nausea and vomiting caused by radiation, granisetron is usually taken within 1 hour before treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take granisetron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What side effects can this medication cause?

Chemotherapy-induced nausea and vomiting CINV , prevention:. Highly emetogenic chemotherapy:. Moderately emetogenic chemotherapy:. Low-emetogenic chemotherapy:. Consult drug interactions database for more information.

Official websites use. Share sensitive information only on official, secure websites. Granisetron is used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. Granisetron is in a class of medications called 5-HT 3 receptor antagonists. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Granisetron comes as a tablet to take by mouth. When taken to prevent nausea and vomiting caused by chemotherapy, granisetron is usually taken 1 hour before chemotherapy is begun.

Granisetron hydrochloride syrup uses

This page contains brief information about granisetron and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials. FDA label information for this drug is available at DailyMed. Granisetron is approved to be used alone or with other drugs to prevent:. Granisetron is also available in a different form called granisetron hydrochloride. MedlinePlus Information on Granisetron - A lay language summary of important information about this drug that may include the following:. Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied. Granisetron Placeholder slot.

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Granisetron may cause side effects. Agonists: BRL Ergolines e. Hypersensitivity to granisetron or any component of the formulation or to other 5-HT3 receptor antagonists. You may also consider taking laxatives for relief and drink plenty of water too. This drug does not have any effect on dopamine receptors or muscarinic receptors. Article Talk. Ann Oncol. Thrombocytopenia, ascites, pulmonary deterioration, and renal and hepatic failure have been reported in premature neonates after receiving parenteral products containing polysorbate 80 Alade ; CDC Cover patch application site with clothing to protect from natural or artificial sunlight exposure while patch is applied and for 10 days following removal; granisetron may potentially be affected by natural or artificial sunlight. May be placed back in refrigerator after being kept at room temperature; may remain at room temperature for a maximum of 7 days. Carlisle J ed. Mechanism of Action Selective 5-HT 3 -receptor antagonist, blocking serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone.

Granisetron is a serotonin 5-HT 3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and radiotherapy.

Palonosetron in the prevention of chemotherapy-induced nausea and vomiting: an evidence-based review of safety, efficacy, and place in therapy. Billio A ed. Wikimedia Commons. Expert advice for Granisetron You have been prescribed Granisetron for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy. Prefilled Syringe Sustol Subcutaneous. Administer only on the day s chemotherapy is administered. It is fast-acting and starts working within 30 minutes. SS has also been reported following overdose of another 5-HT 3 receptor antagonist. Ask your pharmacist for a list of the ingredients. Do not use on red, irritated, or damaged skin. A case of granisetron associated intraoperative cardiac arrest. Product Availability Granisol oral solution has been discontinued in the US for more than 1 year. In general, these changes are not clinically relevant; however, when used in conjunction with other agents that prolong these intervals eg, Class I and III antiarrhythmics , arrhythmia or clinically relevant QT interval prolongation may occur resulting in torsade de pointes. Hypersensitivity reactions, usually a delayed reaction, have been reported following exposure to pharmaceutical products containing polysorbate 80 in certain individuals Isaksson ; Lucente ; Shelley