j exp med

J exp med

Potential mechanisms driving obesity-related inflammation, primarily in adipose tissue and other metabolic organs and implications of circulatory inflammatory factors on various metabolic and regulatory organs, j exp med. Chromosome 15 15q abnormality in patients with Prader-Willi syndrome and Angelman syndrome. WJEM accepts both solicited and unsolicited manuscripts. Articles published in WJEM are high-quality, clinical and basic, influential research articles by established j exp med authors as well as new researchers.

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J exp med

Journal of Experimental Medicine is a monthly peer-reviewed medical journal published by Rockefeller University Press that publishes research papers and commentaries on the physiological , pathological , and molecular mechanisms that encompass the host response to disease. The journal prioritizes studies on intact organisms and has made a commitment to publishing studies on human subjects. The journal has no single editor-in-chief , but thirteen academic editors. Welch , the school's founder and also the first president of the Board of Scientific Directors of the Rockefeller Institute since renamed Rockefeller University. From its inception, Welch edited the journal by himself—even editing manuscripts while attending baseball games. By March , the editorial burden became too great for Welch, who stopped publishing papers and began stockpiling manuscripts and unanswered correspondence in his office, explaining the conspicuous absence of published papers from to In October , Welch appealed to the board of the Rockefeller Institute to take over the journal. The transfer of ownership and publication responsibilities required the physical transfer of manuscripts from Welch's office, which fell to the director of the Rockefeller Institute, Simon Flexner , who carried the abandoned manuscripts from Baltimore to New York City in a suitcase. The first issue published by the Rockefeller Institute appeared in February , with Flexner serving as editor, and the journal has been published regularly since then. Although the journal was adopted by the Rockefeller Institute as a venue for publication of the institute's own research, it also accepted submissions from outside. Even in the early years, more than half of the papers published in the journal came from external labs.

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She has been a professional editor since when she joined Journal of Experimental Medicine as a scientific editor. She then pursued her postdoctoral research with Robert Darnell at The Rockefeller University, focusing on RNA-protein crosstalk in neurological diseases. She pursued her postdoctoral work with Abraham Brass and Kate Fitzgerald at University of Massachusetts Medical School, focusing on uncovering novel host factors in viral replication. She then trained with Dr. Jayanta Chaudhuri at the Sloan Kettering Institute. Throughout her training and appointments, her particular focus has been on many aspects relating to B cell biology.

J exp med

Over the past decade, our view of human-associated microbes has expanded beyond that of a few species toward an appreciation of the diverse and niche-specialized microbial communities that develop in the human host with chronological age. The largest reservoir of microbes exists in the distal gastrointestinal tract, both in the lumen, where microbes facilitate primary and secondary metabolism, and on mucosal surfaces, where they interact with host immune cell populations. While local microbial-driven immunomodulation in the gut is well described, more recent studies have demonstrated a role for the gut microbiome in influencing remote organs and mucosal and hematopoietic immune function.

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Article Talk. Browse All. The paramount objective of WJEM is to showcase and promote distinguished research in the field of experimental medicine, to help advance development of this field. Risk factors for hydroxychloroquine-induced arrhythmia. Search Dropdown Menu. Red cell distribution width: A predictor of the severity of hypertriglyceridemia-induced acute pancreatitis. Review Cancer Focus. March 06 Autoinflammation is marked by IL-1 cytokine overexpression and excessive infiltration by neutrophils. In this Review, Freret and Boire describe the anatomy of the leptomeninges and routes of cancer spread to the CSF, highlighting therapeutic opportunities. Sign In or Create an Account. Exploring the mechanism of action bitter melon in the treatment of breast cancer by network pharmacology. Copyright to articles remains with the authors and third parties may re-use content after 6 months under the terms of a Creative Commons Attribution-Noncommercial-Share Alike 3. The Year in Experimental Medicine.

Adeline E. Walsh , John R. Lukens; Engineering mighty microglia.

Graphical abstract. Academic journal. Skip Nav Destination. From its inception, Welch edited the journal by himself—even editing manuscripts while attending baseball games. WJEM accepts both solicited and unsolicited manuscripts. Read Edit View history. IL promotes skin autoinflammation. Categories : Creative Commons-licensed journals Delayed open access journals Academic journals established in General medical journals Monthly journals establishments in Maryland Rockefeller University Press academic journals. Volume ,. Meningeal lymphatics are conduits for cerebrospinal fluid drainage to lymphatics and lymph nodes in the neck. All content is also deposited in PubMed Central , where it is available to the public six months after publication.

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