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In clinical studies with trazodone hydrochloride, investigators did not find drug-seeking behavior in individuals using the medication. This suggests that trazodone hydrochloride has little to no potential for misuse and dependence. However, you may experience additional side effects if you stop taking it suddenly. Speak with your doctor about quitting or tapering off trazodone to prevent additional side effects. They will explain how to reduce your dose gradually and safely.

Pliva 433

Trazodone is an antidepressant that is sometimes prescribed as a sleep aid. It is not addictive and may offer additional benefits over other sleep aids for certain conditions, such as sleep apnea. Having trouble falling asleep or staying asleep can affect every aspect of your life, from work and play to your health. This medicine works in multiple ways in your body. One of its actions is to regulate the neurotransmitter serotonin , which helps brain cells communicate with each other and influences many activities such as sleep, thoughts, mood, appetite, and behavior. Even at lower doses, trazodone can cause you to feel relaxed, tired, and sleepy. It does this by blocking chemicals in the brain that interact with serotonin and other neurotransmitters , such as, 5-HT2A, alpha1 adrenergic receptors, and H1 histamine receptors. Taking trazodone has increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients. People taking this medication should be closely monitored for worsening symptoms and emergence of suicidal thoughts and behaviors. Trazodone is not approved for use in pediatric patients. Though the FDA has approved trazodone for use as a treatment for depression in adults, for many years doctors have also prescribed it as a sleep aid. The FDA approves medications to treat specific conditions based on clinical trials. When doctors prescribe the medicine for conditions other than what was approved by the FDA, it is known as off-label prescribing. Off-label use of a medication is a widespread practice. Twenty percent of medications are prescribed off-label.

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If you are a consumer or patient please visit this version. Trazodone hydrochloride tablets are a selective serotonin reuptake inhibitor indicated for the treatment of major depressive disorder MDD 1. Starting dose: mg in divided doses daily. May be increased by 50 mg per day every three to four days. Maximum dose: mg per day in divided doses 2. Trazodone hydrochloride tablets should be taken shortly after a meal or light snack 2. Tablets should be swallowed whole or broken in half along the score line, and should not be chewed or crushed 2.

If you are a consumer or patient please visit this version. Trazodone hydrochloride tablets are a selective serotonin reuptake inhibitor indicated for the treatment of major depressive disorder MDD 1. Starting dose: mg in divided doses daily. May be increased by 50 mg per day every three to four days. Maximum dose: mg per day in divided doses 2. Trazodone hydrochloride tablets should be taken shortly after a meal or light snack 2. Tablets should be swallowed whole or broken in half along the score line, and should not be chewed or crushed 2. When discontinued, gradual dose reduction is recommended 2.

Pliva 433

In clinical studies with trazodone hydrochloride, investigators did not find drug-seeking behavior in individuals using the medication. This suggests that trazodone hydrochloride has little to no potential for misuse and dependence. However, you may experience additional side effects if you stop taking it suddenly. Speak with your doctor about quitting or tapering off trazodone to prevent additional side effects. They will explain how to reduce your dose gradually and safely. Over 3 million people use BetterHelp.

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Share this article. Decreases Compared to Placebo. Do not chew or crush trazodone hydrochloride tablets. Labeler - Blenheim Pharmacal, Inc. Signs and symptoms of hyponatremia include headache, difficulty concentrating, memory impairment, confusion, weakness, and unsteadiness, which can lead to falls. Monitor cardiac rhythm and vital signs. Because of this, trazodone hydrochloride is not approved for pediatric patients. Furthermore, limited animal data on the effects of combined use of serotonergic antidepressants and MAOIs suggest that these drugs may act synergistically to elevate blood pressure and evoke behavioral excitation. People taking this medication should be closely monitored for worsening symptoms and emergence of suicidal thoughts and behaviors. Maximum dose: mg per day in divided doses 2. Because trazodone causes drowsiness, which may extend even a day after you take the pill, you must practice caution, especially in activities that require alertness.

This medicine is known as trazodone. Blood tests, imaging tests and more are used to diagnose musculoskeletal disorders.

Symptoms of hyponatremia include: headache, feeling weak, feeling confused, trouble concentrating, memory problems and feeling unsteady when you walk. Concomitant administration of drugs that prolong the QT interval or that are inhibitors of CYP3A4 may increase the risk of cardiac arrhythmia. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Tablets should be swallowed whole or broken in half along the score line, and should not be chewed or crushed 2. Antidepressants, Serotonin Modulators Tablet. They will explain how to reduce your dose gradually and safely. Rx only Tablets. Treatment with trazodone hydrochloride tablets and any concomitant serotonergic or antidopaminergic agents, including antipsychotics, should be discontinued immediately if the above reactions occur and supportive symptomatic treatment should be initiated. What are the possible side effects of trazodone hydrochloride tablets? Trazodone hydrochloride tablets should be swallowed whole or broken in half along the score line. Want to learn more?