Robitussin moa

Manufacturer: Interphil. Full Prescribing Info.

Robitussin DM can help reduce cough and loosen phlegm. It may interact with some medications, including those for certain psychiatric conditions. Robitussin DM is a cough medicine for treating your cold or flu. Robitussin DM is used to temporarily relieve your cough from minor throat irritation or a cold. It also helps loosen phlegm from chest congestion so that you can cough it up and spit it out. Robitussin DM comes in a liquid form that you take by mouth. Dextromethorphan is an antitussive drug used to help relieve constant coughing.

Robitussin moa

Dextromethorphan DXM is a cough suppressant used in many cough and cold medicines. It is in the morphinan class of medications with sedative , dissociative , and stimulant properties at lower doses. Dextromethorphan does not have a significant affinity for the mu-opioid receptor activity typical of morphinan compounds and exerts its therapeutic effects through several other receptors. When exceeding approved dosages, dextromethorphan acts as a dissociative hallucinogen. It has multiple mechanisms of action , including actions as a nonselective serotonin reuptake inhibitor [9] and a sigma-1 receptor agonist. It was patented in and approved for medical use in The primary use of dextromethorphan is as a cough suppressant , for the temporary relief of cough caused by minor throat and bronchial irritation such as commonly accompanies the flu and common cold , or from inhaled particle irritants, as well as chronic cough at a higher dosage. Dextromethorphan is the actual therapeutic agent in the combination; quinidine merely serves to inhibit the enzymatic degradation of dextromethorphan and thereby increase its circulating concentrations via inhibition of CYP2D6. Because dextromethorphan can trigger a histamine release allergic reaction , atopic children, who are especially susceptible to allergic reactions, should be administered dextromethorphan only if absolutely necessary, and only under the strict supervision of a healthcare professional. Side effects of dextromethorphan at normal therapeutic doses can include: [4] [14] [19]. A rare side effect is respiratory depression.

As early asdextromethorphan hydrobromide powder could be purchased in robitussin moa from online retailers, allowing users to avoid consuming dextromethorphan in syrup preparations. PMID Inrobitussin moa, the FDA approved the use of dextromethorphan for pseudobulbar affect in combination with quinidine.

Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf. Dextromethorphan received FDA approval in for its use as a cough suppressant. It is one of the most common compounds found in most over-the-counter antitussives for the past 50 years. In , the FDA approved the use of dextromethorphan for pseudobulbar affect in combination with quinidine.

Dextromethorphan DXM is a cough suppressant used in many cough and cold medicines. It is in the morphinan class of medications with sedative , dissociative , and stimulant properties at lower doses. Dextromethorphan does not have a significant affinity for the mu-opioid receptor activity typical of morphinan compounds and exerts its therapeutic effects through several other receptors. When exceeding approved dosages, dextromethorphan acts as a dissociative hallucinogen. It has multiple mechanisms of action , including actions as a nonselective serotonin reuptake inhibitor [9] and a sigma-1 receptor agonist. It was patented in and approved for medical use in The primary use of dextromethorphan is as a cough suppressant , for the temporary relief of cough caused by minor throat and bronchial irritation such as commonly accompanies the flu and common cold , or from inhaled particle irritants, as well as chronic cough at a higher dosage. Dextromethorphan is the actual therapeutic agent in the combination; quinidine merely serves to inhibit the enzymatic degradation of dextromethorphan and thereby increase its circulating concentrations via inhibition of CYP2D6.

Robitussin moa

Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf.

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How we reviewed this article: Sources. Grapefruit and grapefruit juices especially white grapefruit juice, but also including other citrus fruits such as bergamot and lime , as well as a number of noncitrus fruits [25] generally are recommended to be avoided while using dextromethorphan and numerous other medications. Diagnosis and management of DM overdose require an interprofessional team of healthcare professionals, including clinicians, mid-level practitioners, nurses, pharmacists, and any witnesses or family members. These patients should get referred to the nearest emergency room. It is freely soluble in chloroform and insoluble in water ; the hydrobromide salt is water-soluble up to 1. For example, dextromethorphan can increase the risk of drowsiness in older people. BMJ Case Reports. Serotonin syndrome may result from the combined use of dextromethorphan and serotonergic antidepressants such as selective serotonin reuptake inhibitor SSRIs or monoamine oxidase inhibitor MAOIs. Elsevier BV. It helps stop your cough by decreasing activity in your brain that triggers your impulse to cough. Pediatric Patients: The safety and efficacy of dextromethorphan on infants and very young children less than 4 years are not established by any systemic clinical trials in pediatric patients. Diphenidine Ephenidine Fluorolintane Methoxphenidine. If the patient is not sure if the patient's prescription medication contains one of these drugs, ask a doctor or pharmacist before taking this product.

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The average dose necessary for effective antitussive therapy is between 10 and 45 mg, depending on the individual. J Crit Care. It has been used in counterfeit medications. These stages are commonly referred to as "plateaus". Dextromethorphan does not have a significant affinity for the mu-opioid receptor activity typical of morphinan compounds and exerts its therapeutic effects through several other receptors. Side effects from Robitussin DM. Grade D includes patients with suicidal ideation, intentional abuse, or malicious intent; all should obtain a referral to the nearest emergency department. ISRN Psychiatry. Overall, it is a cost-effective method with moderate reaction conditions that is easy to handle and suitable for industrial production. Administration Dosing and administration of dextromethorphan are mostly via the oral route. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.