Zumla

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Professor Sir Ali Zumla is globally renowned for his leadership of health policy relevant research and for his outstanding and extensive outputs in infectious diseases, tropical medicine, with a focus on TB, HIV and respiratory diseases. New innovations for shortening duration of therapy, improving treatment outcomes, preventing relapse, reducing drug resistance, and preventing long term lung damage, are urgently required. The TB drug pipeline remains sparse. A broad of range of Host Directed Therapies HDT now provide hope for improving treatment outcomes and reducing duration of therapy. These require evaluation in randomized, placebo-controlled clinical trials RCTs as adjuncts to current TB treatment regimens. View All Publications.

Zumla

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Professor Sir Alimuddin Zumla is professor of infectious diseases and international health at University College London. His London and overseas research activities span the interface between clinical investigation and biomedical science, with the long-term goals of understanding the pathogenesis of respiratory tract infections, and emerging and re-emerging infectious diseases with epidemic potential, afflicting adults and children, and developing methods for rapid diagnosis, better treatment and control. Sir Ali's research embraces the principles of evidence-based medicine, contributing knowledge through specific clinical research, and training activities in the UK, Europe and in sub-Saharan African countries. He is visiting professor to several European and African universities and serves on many national and international advisory committees. His global leadership of infectious diseases has earned him numerous prestigious prizes, medals and awards and his work reflects the UK NHS's influence on and contributions to global health. The Lancet.

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Severe acute respiratory syndrome SARS and Middle East respiratory syndrome MERS are examples of emerging zoonotic coronavirus infections capable of person-to-person transmission that result in large-scale epidemics with substantial effects on patient health and socioeconomic factors. Unlike patients with mild illnesses that are caused by other human-pathogenic coronaviruses, patients with SARS or MERS coronavirus infections may develop severe acute respiratory disease with multi-organ failure. Both SARS and MERS pose major clinical management challenges because there is no specific antiviral treatment that has been proven to be effective in randomized clinical trials for either infection. Substantial efforts are underway to discover new therapeutic agents for coronavirus infections. Virus-based therapies include monoclonal antibodies and antiviral peptides that target the viral spike glycoprotein, viral enzyme inhibitors, viral nucleic acid synthesis inhibitors and inhibitors of other viral structural and accessory proteins. Host-based therapies include agents that potentiate the interferon response or affect either host signalling pathways involved in viral replication or host factors utilized by coronaviruses for viral replication.

Zumla

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Infectious Disease Clinics 33 4 , , About Scholar Search help. Isoniazid preventive therapy for children and adolescents in sub-Saharan Africa -obstacles and opportunities. Royal Society of Tropical Medicine and Hygiene. Lamour: Live Chat Make Friends. Zumla A, Niederman MS. International journal of infectious diseases , S7-S12 , The app doesn't work properly for me. A Malaysian science prize awarded to those who have made outstanding contributions to tropical sciences. Pathogenesis studies and epidemiological studies : Sentinel epidemiological and clinical studies have shown the emergence of extensively drug resistant TB. Skip to main content Skip to navigation. Professor Sir Alimuddin Zumla. It is awarded once every three years to senior experts whose contribution to tropical medicine or hygiene is considered to merit the honour most. New articles by this author.

Federal government websites often end in. The site is secure. To review the data presented in the WHO global TB report and discuss the current constraints in the global response.

Burden of tuberculosis at post mortem in inpatients at a tertiary referral centre in sub-Saharan Africa: a prospective descriptive autopsy study. Retrieved 11 November Royal College of Physicians of London. This "Cited by" count includes citations to the following articles in Scholar. Archived from the original on 6 February Tackling long-term morbidity and mortality after successful tuberculosis treatment Lancet Infect Dis. Analytical biochemistry 1 , , Study International. The Lancet. Lancet Planet Health. Your transaction is secure. PMID: Email address for updates.